Emerging Roles of Mast Cells in the Regulation of Lymphatic Immuno-Physiology

"Evidence presented in this review suggests that MCs [Mast Cells] are intricately involved in the regulation of lymphatic functions, thus contributing to the convergence of the immune system with the lymphatic vascular system. Through the secretion of various mediators, cytokines and growth factors, MCs not only facilitate cellular interaction and migration but also influence lymphatic permeability, contractility, and vascular remodeling and immune cell trafficking toward and through the LVs [Lymphatic Vessels]."

Source: Frontiers in Immunology